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1

Enhanced Degradation of Chemical Warfare Agents through Molecular Engineering of the Phosphotriesterase Active Site

Hill, Craig M., Li, Wen-Shan, Thoden, James B., Holden, Hazel M., Raushel, Frank M.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 119 KB

english, 2003

2

Carbamoyl phosphate synthetase: a tunnel runs through it

Hazel M Holden, James B Thoden, Frank M Raushel

Journal:

Current Opinion in Structural Biology

Year:

1998

Language:

english

File:

PDF, 583 KB

english, 1998

3

The Amidotransferase Family of Enzymes: Molecular Machines for the Production and Delivery of Ammonia †

Raushel, Frank M., Thoden, James B., Holden, Hazel M.

Journal:

Year:

1999

Language:

english

File:

PDF, 223 KB

english, 1999

4

Structure of Carbamoyl Phosphate Synthetase: A Journey of 96 Å from Substrate to Product †,‡

Thoden, James B., Holden, Hazel M., Wesenberg, Gary, Raushel, Frank M., Rayment, Ivan

Journal:

Year:

1997

Language:

english

File:

PDF, 1.46 MB

english, 1997

5

Carbamoyl Phosphate Synthetase: Caught in the Act of Glutamine Hydrolysis †,‡

Thoden, James B., Miran, Sophie G., Phillips, James C., Howard, Andrew J., Raushel, Frank M., Holden, Hazel M.

Journal:

Year:

1998

Language:

english

File:

PDF, 151 KB

english, 1998

6

Investigation of a Sugar N -formyltransferase from the Plant Pathogen Pantoea ananatis

Hofmeister, Daniel L., Thoden, James B., Holden, Hazel M.

Journal:

Protein Science

Year:

2019

Language:

english

File:

PDF, 2.87 MB

english, 2019

7

The HighâResolution Structure of a UDPâlâRhamnose Synthase from Acanthamoeba polyphaga Mimivirus

Bockhaus, Nicholas J., Ferek, Justin D., Thoden, James B., Holden, Hazel M.

Journal:

Protein Science

Year:

2020

File:

PDF, 2.93 MB

2020

8

Enzymes with Molecular Tunnels

Frank M. Raushel, James B. Thoden, Hazel M. Holden

Journal:

Year:

2003

File:

PDF, 50 KB

2003

9

Kinetic mechanism of asparagine synthetase from Vibrio cholerae

Vicente Fresquet, James B Thoden, Hazel M Holden, Frank M Raushel

Journal:

Bioorganic Chemistry

Year:

2004

Language:

english

File:

PDF, 243 KB

english, 2004

10

Functional significance of Glu-77 and Tyr-137 within the active site of isoaspartyl dipeptidase

Ricardo Martí-Arbona, James B. Thoden, Hazel M. Holden, Frank M. Raushel

Journal:

Bioorganic Chemistry

Year:

2005

Language:

english

File:

PDF, 251 KB

english, 2005

11

Identification of inhibitors of N5-carboxyaminoimidazole ribonucleotide synthetase by high-throughput screening

Steven M. Firestine, Hanumantharao Paritala, Jane E. Mcdonnell, James B. Thoden, Hazel M. Holden

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 490 KB

english, 2009

12

Carbamoyl phosphate synthetase: a crooked path from substrates to products

Frank M Raushel, James B Thoden, Gregory D Reinhart, Hazel M Holden

Journal:

Current Opinion in Chemical Biology

Year:

1998

Language:

english

File:

PDF, 1.49 MB

english, 1998

13

High-resolution X-ray structure of UDP-galactose 4-epimerase complexed with UDP-phenol

James B. Thoden, Perry A. Frey, Hazel M. Holden

Journal:

Protein Science

Year:

1996

Language:

english

File:

PDF, 10.61 MB

english, 1996

14

Structure of the β2 homodimer of bacterial luciferase from vibrio harveyi: X-ray analysis of a kinetic protein folding trap

James B. Thoden, Hazel M. Holden, Andrew J. Fisher, James F. Sinclair, Gary Wesenberg, Thomas O. Baldwin, Ivan Rayment

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 8.53 MB

english, 1997

15

Effect of inspiratory resistance to prolonged exercise in a hot environment wearing protective clothing

Maurice Jetté, Josée Quenneville, James Thoden, Sydney Livingstone

Journal:

International Journal of Biometeorology

Year:

1992

Language:

english

File:

PDF, 572 KB

english, 1992

16

Headache pain model for assessing and comparing the efficacy of over-the-counter analgesic agents

Schachtel, Bernard P, Thoden, William R, Konerman, James P, Brown, Ann, Chaing, Danny S

Journal:

Clinical Pharmacology & Therapeutics

Year:

1991

Language:

english

File:

PDF, 1001 KB

english, 1991

17

The catalytic mechanism of galactose mutarotase

James B. Thoden, Jungwook Kim, Frank M. Raushel, Hazel M. Holden

Journal:

Protein Science

Year:

2003

Language:

english

File:

PDF, 1.20 MB

english, 2003

18

The structure of GDP-4-keto-6-deoxy-d-mannose-3-dehydratase: A unique coenzyme B6-dependent enzyme

Paul D. Cook, James B. Thoden, Hazel M. Holden

Journal:

Protein Science

Year:

2006

Language:

english

File:

PDF, 1.31 MB

english, 2006

19

The molecular architecture of glucose-1-phosphate uridylyltransferase

James B. Thoden, Hazel M. Holden

Journal:

Protein Science

Year:

2007

Language:

english

File:

PDF, 725 KB

english, 2007

20

Molecular architecture of DesV from Streptomyces venezuelae: A PLP-dependent transaminase involved in the biosynthesis of the unusual sugar desosamine

E. Sethe Burgie, James B. Thoden, Hazel M. Holden

Journal:

Protein Science

Year:

2007

Language:

english

File:

PDF, 932 KB

english, 2007

21

Active site geometry of glucose-1-phosphate uridylyltransferase

James B. Thoden, Hazel M. Holden

Journal:

Protein Science

Year:

2007

Language:

english

File:

PDF, 1.06 MB

english, 2007

22

Physiological effects of inspiratory resistance on progressive aerobic work

Maurice Jetté, James Thoden, Sidney Livingstone

Journal:

European Journal of Applied Physiology

Year:

1990

Language:

english

File:

PDF, 606 KB

english, 1990

23

Biosynthetic enzymes of unusual microbial sugars

Hazel M Holden, Paul D Cook, James B Thoden

Journal:

Current Opinion in Structural Biology

Year:

2010

Language:

english

File:

PDF, 541 KB

english, 2010

24

Steroidal allylic fluorination using diethylaminosulfur trifluoride: A convenient method for the synthesis of 3β-acetoxy-7α-and 7β-fluoroandrost-5-en-17-one

Padma Marwah, James B. Thoden, Douglas R. Powell, Henry A. Lardy

Journal:

Year:

1996

Language:

english

File:

PDF, 698 KB

english, 1996

25

Functional characterization of the K257R and G319E-hGALE alleles found in patients with ostensibly peripheral epimerase deficiency galactosemia

Jamie Wasilenko, Mary E. Lucas, James B. Thoden, Hazel M. Holden, Judith L. Fridovich-Keil

Journal:

Molecular Genetics and Metabolism

Year:

2005

Language:

english

File:

PDF, 688 KB

english, 2005

26

Three-Dimensional Structure of Escherichia coli Asparagine Synthetase B: A Short Journey from Substrate to Product †,‡

Larsen, Todd M., Boehlein, Susan K., Schuster, Sheldon M., Richards, Nigel G. J., Thoden, James B., Holden, Hazel M., Rayment, Ivan

Journal:

Year:

1999

Language:

english

File:

PDF, 1.25 MB

english, 1999

27

Enzymes with Molecular Tunnels

Raushel, Frank M., Thoden, James B., Holden, Hazel M.

Journal:

Accounts of Chemical Research

Year:

2003

Language:

english

File:

PDF, 1.09 MB

english, 2003

28

Long-range allosteric transitions in carbamoyl phosphate synthetase

James B. Thoden, Xinyi Huang, Jungwook Kim, Frank M. Raushel, Hazel M. Holden

Journal:

Protein Science

Year:

2004

Language:

english

File:

PDF, 313 KB

english, 2004

29

Increasing Exercise Duration Does Not Affect the Postexercise Elevation in Esophageal Temperature

Kenny, Glen P., Denis, Paul M., Boulé, Normand G., Proulx, Carolyn E., Thoden, James S., Reardon, Francis D.

Journal:

Canadian Journal of Applied Physiology

Year:

1999

Language:

english

File:

PDF, 1.14 MB

english, 1999

30

Molecular Architecture of a C- 3′-Methyltransferase Involved in the Biosynthesis of d -Tetronitrose

Bruender, Nathan A., Thoden, James B., Kaur, Manpreet, Avey, Marie K., Holden, Hazel M.

Journal:

Year:

2010

Language:

english

File:

PDF, 3.42 MB

english, 2010

31

Structural Analysis of UDP-Sugar Binding to UDP-Galactose 4-Epimerase from Escherichia coli †,‡

Thoden, James B., Hegeman, Adrian D., Wesenberg, Gary, Chapeau, Marie C., Frey, Perry A., Holden, Hazel M.

Journal:

Year:

1997

Language:

english

File:

PDF, 771 KB

english, 1997

32

X-ray Structure of KijD3, a Key Enzyme Involved in the Biosynthesis of d -Kijanose

Bruender, Nathan A., Thoden, James B., Holden, Hazel M.

Journal:

Year:

2010

Language:

english

File:

PDF, 4.86 MB

english, 2010

33

Experimental/theoretical studies of the paramagnetic 52/53-electron triangular metal [Ni3(.eta.5-C5H5)3(.mu.3-S)2]n series (n = 1+, 0) containing weak metal-metal bonding interactions: Fenske-Hall MO analysis of the trimetal-antibonding frontier orbitals involved in the reversible redox-generated change in nickel-sulfur Ni3S2 core geometry

North, Terry E., Thoden, James B., Spencer, Brock, Dahl, Lawrence F.

Journal:

Organometallics

Year:

1993

Language:

english

File:

PDF, 1.98 MB

english, 1993

34

X-ray Structures of the MgADP, MgATPγS, and MgAMPPNP Complexes of the Dictyostelium discoideum Myosin Motor Domain †,‡

Gulick, Andrew M., Bauer, Cary B., Thoden, James B., Rayment, Ivan

Journal:

Year:

1997

Language:

english

File:

PDF, 634 KB

english, 1997

35

Structural and Biochemical Characterization of a Bifunctional Ketoisomerase/ N -Acetyltransferase from Shewanella denitrificans

Chantigian, Daniel P., Thoden, James B., Holden, Hazel M.

Journal:

Year:

2013

Language:

english

File:

PDF, 729 KB

english, 2013

36

pH-rate profiles support a general base mechanism for galactokinase (Lactococcus lactis)

Reinhardt, Laurie A., Thoden, James B., Peters, Greg S., Holden, Hazel M., Cleland, W.W.

Journal:

Year:

2013

Language:

english

File:

PDF, 1013 KB

english, 2013

37

Aerobic Exercise Prescription Intensity in Terms of Maximal Working Capacity

MAURICE JETTÉ, JAMES S. THODEN and ROGER GAUTHIER

Journal:

Canadian Journal of Public Health / Revue Canadienne de Sante'e Publique

Year:

1975

Language:

english

File:

PDF, 699 KB

english, 1975

38

Molecular Structures of the S124A, S124T, and S124V Site-Directed Mutants of UDP-galactose 4-Epimerase from Escherichia coli †,‡

Thoden, James B., Gulick, Andrew M., Holden, Hazel M.

Journal:

Year:

1997

Language:

english

File:

PDF, 1.12 MB

english, 1997

39

High-Resolution X-Ray Structure of Isoaspartyl Dipeptidase from Escherichia coli †,‡

Thoden, James B., Marti-Arbona, Ricardo, Raushel, Frank M., Holden, Hazel M.

Journal:

Year:

2003

Language:

english

File:

PDF, 652 KB

english, 2003

40

Structural and Functional Studies of Aspergillus clavatus N 5 -Carboxyaminoimidazole Ribonucleotide Synthetase,

Thoden, James B., Holden, Hazel M., Paritala, Hanumantharao, Firestine, Steven M.

Journal:

Year:

2010

Language:

english

File:

PDF, 3.95 MB

english, 2010

41

Molecular Structure of Dihydroorotase: A Paradigm for Catalysis through the Use of a Binuclear Metal Center †,‡

Thoden, James B., Phillips,, George N., Neal, Tamiko M., Raushel, Frank M., Holden, Hazel M.

Journal:

Year:

2001

Language:

english

File:

PDF, 661 KB

english, 2001

42

The Small Subunit of Carbamoyl Phosphate Synthetase: Snapshots along the Reaction Pathway †

Thoden, James B., Huang, Xinyi, Raushel, Frank M., Holden, Hazel M.

Journal:

Year:

1999

Language:

english

File:

PDF, 548 KB

english, 1999

43

Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o -Succinylbenzoate Synthase from Amycolatopsis †,‡

Thoden, James B., Taylor Ringia, Erika A., Garrett, James B., Gerlt, John A., Holden, Hazel M., Rayment, Ivan

Journal:

Year:

2004

Language:

english

File:

PDF, 1.45 MB

english, 2004

44

Production of a Novel N -Monomethylated Dideoxysugar

Thoden, James B., Holden, Hazel M.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.37 MB

english, 2014

45

Three-Dimensional Structure of ATP:Corrinoid Adenosyltransferase from Salmonella typhimurium in Its Free State, Complexed with MgATP, or Complexed with Hydroxycobalamin and MgATP †,‡

Bauer, Cary B., Fonseca, Maris V., Holden, Hazel M., Thoden, James B., Thompson, Thomas B., Escalante-Semerena, Jorge C., Rayment, Ivan

Journal:

Year:

2001

Language:

english

File:

PDF, 1.15 MB

english, 2001

46

Structural Analysis of the Active Site Geometry of N 5 -Carboxyaminoimidazole Ribonucleotide Synthetase from Escherichia coli †,‡

Thoden, James B., Holden, Hazel M., Firestine, Steven M.

Journal:

Year:

2008

Language:

english

File:

PDF, 6.73 MB

english, 2008

47

Polydentate ligands containing phosphorus. 14. Synthesis and molecular structure of (1,5-cyclooctadiene)[bis(diphenylphosphinoyl)(diphenylthiophosphinoyl)methanido]rhodium(I) 2-propanol, (COD)Rh{[(O)PPh2]2[(S)PPh2]C}.cntdot.i-PrOH

Grim, Samuel O., Kettler, Peter B., Thoden, James B.

Journal:

Organometallics

Year:

1991

Language:

english

File:

PDF, 679 KB

english, 1991

48

Rhodococcus l -Phenylalanine Dehydrogenase: Kinetics, Mechanism, and Structural Basis for Catalytic Specifity †,‡

Brunhuber, Norbert M. W., Thoden, James B., Blanchard, John S., Vanhooke, Janeen L.

Journal:

Year:

2000

Language:

english

File:

PDF, 443 KB

english, 2000

49

X-ray Structures of the Myosin Motor Domain of Dictyostelium discoideum Complexed with MgADP.cntdot.BeFx and MgADP.cntdot.AlF4-

Fisher, Andrew J., Smith, Clyde A., Thoden, James, Smith, Robert, Sutoh, Kazuo, Holden, Hazel M., Rayment, Ivan

Journal:

Year:

1995

Language:

english

File:

PDF, 4.97 MB

english, 1995

50

Synthesis and stereophysical characterization of the Fischer-Palm-related 49-electron thiocarbonyl-capped triangular nickel clusters Ni3(.eta.5-C5H5-xMex)3(.mu.3-X)(.mu.3-Y) (x = 0, 1), containing .pi.-acceptor X and Y capping Ligands (X = Y = CS; X = CS, Y = CO): comparative experimental/theoretical analysis of the triply bridging carbonyl and thiocarbonyl ligands in analogous molecular environments

North, Terry E., Thoden, James B., Spencer, Brock, Bjarnason, Asgeir, Dahl, Lawrence F.

Journal:

Organometallics

Year:

1992

Language:

english

File:

PDF, 2.11 MB

english, 1992

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